Christopher Alteri, Ph.D.

Associate Professor of Biology and Microbiology
Christopher Alteri
College of Arts, Sciences, and Letters
Natural Sciences

Teaching Areas:

Microbiology, Biological Sciences

Research Areas:

Microbiology, Molecular Biology, Pathogenic Escherichia coli, Proteus mirabilis, Swarming, Type VI secretion, UTI

Biography and Education

  • Postdoctoral Fellowship at University of Michigan Medical School, Ann Arbor
  • Ph.D. Microbiology and Immunology, University of Arizona College of Medicine
  • B.S. Microbiology and Chemistry, University of Arizona

Dr. Alteri joined the Natural Sciences faculty in 2018.  Prior to joining the faculty, he was a Research Faculty at the University of Michigan Medical School for 10 years.  Dr. Alteri maintains active collaborations with a number of labs at the medical school in Ann Arbor and has a long-standing commitment to undergraduate research in his laboratory.  His main area of expertise is bacterial pathogenesis and infectious diseases.  His laboratory focuses on understanding interbacterial competition between pathogens, specifically focusing on the specialized secretion system known as the Type VI secretion system.  The T6SS is a weapon deployed by bacteria to directly attack and kill competitors.  Another aspect of his research involves exploring host-microbe interactions with pathogenic E. coli.

Link to Dr. Alteri’s publications

Link to Dr. Alteri's ResearcherID profile

Selected Publications

  • Alteri CJ, Himpsl SD, Zhu K, Hershey HL, Musili N, Miller JE, Mobley HLT. Subtle variation within conserved effector operon gene products contributes to T6SS-mediated killing and immunity. PLoS Pathog. 2017 Nov 20;13(11):e1006729. doi: 10.1371/journal.ppat.1006729. eCollection 2017 Nov. PubMed PMID: 29155899; PubMed Central PMCID: PMC5714391.
  • Alteri CJ, Mobley HL. The Versatile Type VI Secretion System. Microbiol Spectr. 2016 Apr;4(2). doi: 10.1128/microbiolspec.VMBF-0026-2015. Review. PubMed  PMID: 27227310; PubMed Central PMCID: PMC4887148.
  • Mobley HL, Alteri CJ. Development of a Vaccine against Escherichia coli Urinary Tract Infections. Pathogens. 2015 Dec 31;5(1). pii: E1. doi: 10.3390/pathogens5010001. PubMed PMID: 26729174; PubMed Central PMCID: PMC4810122.
  • Alteri CJ, Mobley HLT. Metabolism and Fitness of Urinary Tract Pathogens. Microbiol Spectr. 2015 Jun;3(3). doi: 10.1128/microbiolspec.MBP-0016-2015. PubMed PMID: 26185076; PubMed Central PMCID: PMC4510461.
  • Alteri CJ, Himpsl SD, Mobley HL. Preferential use of central metabolism in vivo reveals a nutritional basis for polymicrobial infection. PLoS Pathog. 2015 Jan 8;11(1):e1004601. doi: 10.1371/journal.ppat.1004601. eCollection 2015 Jan. PubMed PMID: 25568946; PubMed Central PMCID: PMC4287612.
  • Alteri CJ, Himpsl SD, Pickens SR, Lindner JR, Zora JS, Miller JE, Arno PD, Straight SW, Mobley HL. Multicellular bacteria deploy the type VI secretion system to preemptively strike neighboring cells. PLoS Pathog. 2013;9(9):e1003608. doi: 10.1371/journal.ppat.1003608. Epub 2013 Sep 5. PubMed PMID: 24039579; PubMed Central PMCID: PMC3764213.